Process simulation and data modeling in solid oral drug development and manufacture /
Process simulation and data modeling in solid oral drug development and manufacture /
edited by Marianthi G. Ierapetritou and Rohit Ramachandran.
- New York : Human Press : Springer, ©2016.
- 1 online resource (x, 393 pages) : illustrations (some color)
- Methods in pharmacology and toxicology, 1940-6053 .
- Methods in pharmacology and toxicology. .
Includes bibliographical references and index.
Applications of modeling in oral solid dosage form development and manufacturing / Population balance models for pharmaceutical processes / Quantitative approach to understand raw material variability / Discrete element modeling of solid dosage manufacturing processes / Procedure for developing quantitative near infrared (NIR) methods for pharmaceutical products / Advanced process decision making using multivariate latent variable methods / Advanced control of continuous pharmaceutical tablet manufacturing processes / Mathematical tools for the quantitative definition of a design space / Optimization methodologies for the production of pharmaceutical products / Overview of pharmaceutical manufacturing for solid dosage forms / Olav Lyngberg [and others] -- Anwesha Chaudhury [and others] -- Sara Koynov and Fernando J. Muzzio -- Dana Barrasso and Rohit Ramachandran -- Rodolfo J. Romanach, Andres D. Roma n-Ospino, and Manel Alcala -- Matteo Ottavian, Emanuele Tomba, and Massimiliano Barolo -- Ravendra Singh [and others] -- Amanda Rogers and Marianthi G. Ierapetritou -- M. Sebastian Escotet-Espinoza, Amanda Rogers, and Marianthi G. Ierapetritou -- Stephan Sacher and Johannes G. Khinast.
This thorough volume aims to provide pharmaceutical engineers with an introduction to the current state of the art in modeling and simulation of pharmaceutical processes and to summarize a number of practical applications of relevant methodologies in drug product development. Chapters include explorations of simulation and modeling methodologies, data collection and analysis, development of novel sensing techniques, development and integration of individual unit models, optimization approaches for data-based models, design space evaluation techniques, informatics-based methodologies, and emerging topics in pharmaceutical process development. As a part of the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and implementation advice that will make the transition into the laboratory as smooth as possible. Authoritative and cutting edge, Process Simulation and Data Modeling in Solid Oral Drug Development and Manufacture seeks to promote research into process systems methodologies and their application in pharmaceutical product and process development, which will undoubtedly become an increasingly important area in the future.
9781493929962 1493929968
12424827 ybp
101676130 DNLM
Pharmacology.
Drug Delivery Systems
Pharmacology
Pharmacologie.
pharmacology.
Pharmacology
Laboratory Manual
Laboratory manuals.
Manuels de laboratoire.
RM300
615.1
2016 A-663 QV 778
Includes bibliographical references and index.
Applications of modeling in oral solid dosage form development and manufacturing / Population balance models for pharmaceutical processes / Quantitative approach to understand raw material variability / Discrete element modeling of solid dosage manufacturing processes / Procedure for developing quantitative near infrared (NIR) methods for pharmaceutical products / Advanced process decision making using multivariate latent variable methods / Advanced control of continuous pharmaceutical tablet manufacturing processes / Mathematical tools for the quantitative definition of a design space / Optimization methodologies for the production of pharmaceutical products / Overview of pharmaceutical manufacturing for solid dosage forms / Olav Lyngberg [and others] -- Anwesha Chaudhury [and others] -- Sara Koynov and Fernando J. Muzzio -- Dana Barrasso and Rohit Ramachandran -- Rodolfo J. Romanach, Andres D. Roma n-Ospino, and Manel Alcala -- Matteo Ottavian, Emanuele Tomba, and Massimiliano Barolo -- Ravendra Singh [and others] -- Amanda Rogers and Marianthi G. Ierapetritou -- M. Sebastian Escotet-Espinoza, Amanda Rogers, and Marianthi G. Ierapetritou -- Stephan Sacher and Johannes G. Khinast.
This thorough volume aims to provide pharmaceutical engineers with an introduction to the current state of the art in modeling and simulation of pharmaceutical processes and to summarize a number of practical applications of relevant methodologies in drug product development. Chapters include explorations of simulation and modeling methodologies, data collection and analysis, development of novel sensing techniques, development and integration of individual unit models, optimization approaches for data-based models, design space evaluation techniques, informatics-based methodologies, and emerging topics in pharmaceutical process development. As a part of the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and implementation advice that will make the transition into the laboratory as smooth as possible. Authoritative and cutting edge, Process Simulation and Data Modeling in Solid Oral Drug Development and Manufacture seeks to promote research into process systems methodologies and their application in pharmaceutical product and process development, which will undoubtedly become an increasingly important area in the future.
9781493929962 1493929968
12424827 ybp
101676130 DNLM
Pharmacology.
Drug Delivery Systems
Pharmacology
Pharmacologie.
pharmacology.
Pharmacology
Laboratory Manual
Laboratory manuals.
Manuels de laboratoire.
RM300
615.1
2016 A-663 QV 778