Epigenetic reprogramming during mouse embryogenesis : methods and protocols /

Epigenetic reprogramming during mouse embryogenesis : methods and protocols / edited by Katia Ancelin, Maud Borensztein. - 1 online resource (1 PDF file (xi, 318 pages)) : illustrations. - Springer protocols Methods in molecular biology, volume 2214 1940-6029 ; . - Methods in molecular biology (Clifton, N.J.) ; v. 2214. Springer protocols (Series) .

Includes bibliographical references and index.

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Epigenetic reprogramming is crucial for mammalian development and entails unique changes in the spatial and functional organization of the chromatin landscape. Genome-wide reprogramming occurs at specific developmental stages, in the germline and early embryo, and is critical for generating a totipotent/pluripotent state. Although optimized for mouse embryos, these protocols can be adapted to other mammalian models and organoids in culture. Ultimately, this volume aims to present a comprehensive overview of the methods available to scientists wishing to make new discoveries in the fascinating field of chromatin reprogramming.


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9781071609583 1071609580

10.1007/978-1-0716-0958-3 doi

com.springer.onix.9781071609583 Springer Nature

GBC0I2443 bnb

9918248005106676 DNLM 019951616 Uk


Embryology--Laboratory manuals.
Epigenetics--Laboratory manuals.
Mice.
Epigenesis, Genetic
Embryonic Development--genetics
Models, Animal
Mice
Épigénétique--Manuels de laboratoire.
Souris.
Embryons--Développement--Manuels de laboratoire.
Genetics (non-medical).
Biology, life sciences.
Developmental biology.
Science--Life Sciences--Genetics & Genomics.
Science--Life Sciences--Biology--General.
Science--Life Sciences--Biology--Developmental Biology.
Mice
Embryology
Epigenetics


Laboratory Manual
Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.

QL957

571.8/6

W1 / ME9616J v.2214 2021 QU 25

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