Simulations in medicine : pre-clinical and clinical applications /
Simulations in medicine : pre-clinical and clinical applications /
Irena Roterman-Konieczna, (ed.).
- 1 online resource
Includes bibliographical references and index.
Preface ; List of authors ; Part I: Molecular level ; 1. Selected aspects of biological network analysis ; 1.1 Introduction ; 1.2 Selected biological databases ; 1.2.1 Case study: Gene Expression Omnibus ; 1.2.2 RegulonDB ; 1.3 Types of biological networks. 1.3.1 Relations between molecules and types of networks 1.3.2 Biochemical pathways ; 1.4 Network development models ; 1.4.1 Selected tools for assembling networks on the basis of gene expression data ; 1.4.2 Selected tools for reconstruction of networks via literature mining. 1.5 Network analysis 1.5.1 Selected tools ; 1.5.2 Cytoscape analysis examples ; 1.6 Summary ; Part II: Cellular level ; 2. Negative feedback inhibition -- Fundamental biological regulation in cells and organisms ; 2.1 Negative feedback-based systems simulations ; 2.1.1 Introduction. 2.1.2 Glossary of Terms 2.1.3 Software model ; 2.1.4 Application manual ; 2.1.5 OS model example ; 2.1.6 Simulation algorithm ; 3. Information -- A tool to interpret the biological phenomena ; Part III: Organ level ; 4. The virtual heart. 5. Modeling figure/ground separation with spiking neurons 5.1 Introduction ; 5.2 Figure/ground separation ; 5.3 Spiking neural networks ; 5.4 Lateral connections via gap junctions ; 5.5 Simulation of a sheet of laterally connected neurons ; 5.6 Basis of our model ; 5.7 Conclusion.
This book describes biological and medical phenomena and how they can be virtually simulated by breaking them down into basic principles. It introduces a wide spectrum of applications, from molecules, tissues, and organs up to the whole body, with a focus on how to use and interpret these simulations. The book is complemented by topics such as serious games and distance medicine.
English.
9783110406344 3110406349 9783110412390 311041239X
10.1515/9783110406344 doi
876181 MIL
1066332819 DE-101
Medicine--Simulation methods.
Medicine--Computer simulation.
Digital computer simulation.
Computer simulation.
Computer Simulation
Médecine--Méthodes de simulation.
Médecine--Simulation par ordinateur.
Simulation par ordinateur.
simulation.
HEALTH & FITNESS--Holism.
HEALTH & FITNESS--Reference.
MEDICAL--Alternative Medicine.
MEDICAL--Atlases.
MEDICAL--Essays.
MEDICAL--Family & General Practice.
MEDICAL--Holistic Medicine.
MEDICAL--Osteopathy.
Digital computer simulation
Computer simulation
Medicine--Computer simulation
R859.7.C65 / S56 2015
610.1/13
2015 L-153 W 18
Includes bibliographical references and index.
Preface ; List of authors ; Part I: Molecular level ; 1. Selected aspects of biological network analysis ; 1.1 Introduction ; 1.2 Selected biological databases ; 1.2.1 Case study: Gene Expression Omnibus ; 1.2.2 RegulonDB ; 1.3 Types of biological networks. 1.3.1 Relations between molecules and types of networks 1.3.2 Biochemical pathways ; 1.4 Network development models ; 1.4.1 Selected tools for assembling networks on the basis of gene expression data ; 1.4.2 Selected tools for reconstruction of networks via literature mining. 1.5 Network analysis 1.5.1 Selected tools ; 1.5.2 Cytoscape analysis examples ; 1.6 Summary ; Part II: Cellular level ; 2. Negative feedback inhibition -- Fundamental biological regulation in cells and organisms ; 2.1 Negative feedback-based systems simulations ; 2.1.1 Introduction. 2.1.2 Glossary of Terms 2.1.3 Software model ; 2.1.4 Application manual ; 2.1.5 OS model example ; 2.1.6 Simulation algorithm ; 3. Information -- A tool to interpret the biological phenomena ; Part III: Organ level ; 4. The virtual heart. 5. Modeling figure/ground separation with spiking neurons 5.1 Introduction ; 5.2 Figure/ground separation ; 5.3 Spiking neural networks ; 5.4 Lateral connections via gap junctions ; 5.5 Simulation of a sheet of laterally connected neurons ; 5.6 Basis of our model ; 5.7 Conclusion.
This book describes biological and medical phenomena and how they can be virtually simulated by breaking them down into basic principles. It introduces a wide spectrum of applications, from molecules, tissues, and organs up to the whole body, with a focus on how to use and interpret these simulations. The book is complemented by topics such as serious games and distance medicine.
English.
9783110406344 3110406349 9783110412390 311041239X
10.1515/9783110406344 doi
876181 MIL
1066332819 DE-101
Medicine--Simulation methods.
Medicine--Computer simulation.
Digital computer simulation.
Computer simulation.
Computer Simulation
Médecine--Méthodes de simulation.
Médecine--Simulation par ordinateur.
Simulation par ordinateur.
simulation.
HEALTH & FITNESS--Holism.
HEALTH & FITNESS--Reference.
MEDICAL--Alternative Medicine.
MEDICAL--Atlases.
MEDICAL--Essays.
MEDICAL--Family & General Practice.
MEDICAL--Holistic Medicine.
MEDICAL--Osteopathy.
Digital computer simulation
Computer simulation
Medicine--Computer simulation
R859.7.C65 / S56 2015
610.1/13
2015 L-153 W 18