MARC details
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07101cam a2201021 i 4500 |
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ocn846559483 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250702165850.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn|008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
110729s2011 njua obd 001 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
NUI |
| Language of cataloging |
eng |
| Description conventions |
pn |
| Transcribing agency |
NUI |
| Modifying agency |
OCLCQ |
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OCLCO |
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CUV |
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UBY |
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VVL |
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YDXCP |
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QCL |
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EUW |
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VVL |
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PFM |
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OCLCQ |
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CAUOI |
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VT2 |
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UAB |
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LIP |
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OCLCQ |
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TFH |
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OCLCO |
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AU@ |
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OCLCA |
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BUF |
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OCLCO |
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OCLCQ |
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OCLCO |
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CASUM |
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U3W |
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OCLCO |
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OCLCO |
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ESU |
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OCLCQ |
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ADU |
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WURST |
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OCLCA |
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OCLCQ |
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OCLCO |
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OCLCQ |
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OCL |
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OCLCO |
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WSU |
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OCLCO |
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OCLCL |
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OCLCQ |
| 019 ## - |
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752195522 |
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853260259 |
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859634265 |
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870972878 |
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889153403 |
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990417685 |
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1011733825 |
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1027489426 |
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1045327340 |
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1050735330 |
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1087296741 |
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1113206805 |
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1485288637 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781617792045 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
1617792047 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Canceled/invalid ISBN |
9781617792038 |
| Qualifying information |
(p-ISBN) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Canceled/invalid ISBN |
1617792039 |
| Qualifying information |
(p-ISBN) |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-1-61779-204-5 |
| Source of number or code |
doi |
| 029 1# - (OCLC) |
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| OCLC library identifier |
AU@ |
| System control number |
000060907773 |
| 029 1# - (OCLC) |
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| OCLC library identifier |
NZ1 |
| System control number |
16091791 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)846559483 |
| Canceled/invalid control number |
(OCoLC)752195522 |
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(OCoLC)853260259 |
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(OCoLC)859634265 |
| -- |
(OCoLC)870972878 |
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(OCoLC)889153403 |
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(OCoLC)990417685 |
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(OCoLC)1011733825 |
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(OCoLC)1027489426 |
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(OCoLC)1045327340 |
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(OCoLC)1050735330 |
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(OCoLC)1087296741 |
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(OCoLC)1113206805 |
| -- |
(OCoLC)1485288637 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH345 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QD415-436 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
QU 136 P965 2011 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
PSB |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI007000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
572 |
| Edition number |
23 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
MAIN |
| 245 00 - TITLE STATEMENT |
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| Title |
Proprotein convertases / |
| Statement of responsibility, etc. |
edited by Majambu Mbikay, Nabil G. Seidah. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Totowa, NJ : |
| Name of publisher, distributor, etc. |
Humana Press, |
| Date of publication, distribution, etc. |
2011. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource (XI, 367 pages 81 illustrations, 15 illustrations in color.) |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Methods in molecular biology, |
| International Standard Serial Number |
1064-3745 ; |
| Volume/sequential designation |
v. 768 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
On the Discovery of Precursor Processing -- The Prohormone Theory and the Proprotein Convertases: It Is All About Serendipity -- The Proprotein Convertases, 20 Years Later -- Insights from Bacterial Subtilases into the Mechanisms of Intramolecular Chaperone-Mediated Activation of Furin -- The Novel Role of Cathepsin L for Neuropeptide Production Illustrated by Research Strategies in Chemical Biology with Protease Gene Knockout and Expression -- In Vitro Assay for Protease Activity of Proprotein Convertase Subtilisin Kexins (PCSKs): An Overall Review of Existing and New Methodologies -- Inhibitor Screening of Proprotein Convertases Using Positional Scanning Libraries -- Analyses of PCSK9 Post-Translational Modifications Using Time-of-Flight Mass Spectrometry -- The Molecular Biology of Furin-Like Proprotein Convertases in Vascular Remodelling -- Identification of the Myosin Heavy Polypeptide 9 as a Downstream Effector of the Proprotein Convertases in the Human Colon Carcinoma HT-29 Cells -- Regulation of 7B2 mRNA Translation: Dissecting the Role of Its 5'-Untranslated Region -- Analysis of Epigenetic Alterations to Proprotein Convertase Genes in Disease -- Genetic and Functional Characterization of PCSK1 -- Prohormone Processing in Zebrafish -- Use of Zebrafish and Knockdown Technology to Define Proprotein Convertase Activity -- Characterization of Impaired Processing of Neuropeptides in the Brains of Endoproteases Knockout Mice -- Quantitative Peptidomics of Mice Lacking Peptide-Processing Enzymes -- A Proteomic Protocol to Identify Physiological Substrates of Proprotein Convertases -- Neurophenotyping Genetically-Modified Mice for Social Behavior. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Today, activation endoproteolysis of secretory proteins is recognized as a fundamental biological mechanism of spatial and temporal regulation of protein activity as well as of diversification of protein functions. In Proprotein Convertases, experts in the field examine detailed methods involving proprotein convertases, the enzymes mediating this endoproteolysis, which reside within or cycle between the various compartments of the secretory pathway. Providing a timely assessment of impact of activation/inactivation endoproteolysis in the secretory pathway, the volume offers a broader perspective on the biochemistry of the PCSKs (proprotein convertases, subtilisin/kexin-type) by exploring structural and functional analogies with bacterial subtilisin and on the enzymology of endoproteolysis itself by describing the involvement in the process of non-PCSK-type such as cathepsin L. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their specific topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Meticulous and up-to-date, Proprotein Convertases represents an instructive and useful reference book for all scientists interested in endoproteolytic activation and/or inactivation of secretory proproteins through limited proteolysis, for experts in the field and newcomers to it as well. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references and index. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein precursors. |
| 9 (RLIN) |
80230 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proprotein convertases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Hydrolases. |
| 9 (RLIN) |
83156 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymes. |
| 9 (RLIN) |
81046 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Peptide Hydrolases |
| 9 (RLIN) |
83155 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Hydrolases |
| 9 (RLIN) |
83156 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymes |
| 9 (RLIN) |
81046 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymes and Coenzymes |
| 9 (RLIN) |
81544 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Chemicals and Drugs |
| 9 (RLIN) |
13222 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proprotein Convertases |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein Precursors |
| 9 (RLIN) |
80230 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Précurseurs de protéine. |
| 9 (RLIN) |
969982 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proprotéines convertases. |
| 9 (RLIN) |
970720 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Hydrolases. |
| 9 (RLIN) |
83156 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymes. |
| 9 (RLIN) |
81046 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
enzyme. |
| Source of heading or term |
aat |
| 9 (RLIN) |
966124 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Hydrolases |
| Source of heading or term |
fast |
| 9 (RLIN) |
83156 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymes |
| Source of heading or term |
fast |
| 9 (RLIN) |
81046 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proprotein convertases |
| Source of heading or term |
fast |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein precursors |
| Source of heading or term |
fast |
| 9 (RLIN) |
80230 |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
enzymologie |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
enzymology |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
biochemie |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
biochemistry |
| 653 00 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
eiwitten |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
proteins |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
biosynthese |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
biosynthesis |
| 653 10 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Proteins and Enzymes |
| 653 10 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Eiwitten en enzymen |
| 655 #2 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Laboratory Manual |
| 655 #2 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Dictionary |
| 9 (RLIN) |
142581 |
| 655 #4 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Internet Resources. |
| 9 (RLIN) |
80513 |
| 655 #4 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Index not Present. |
| 655 #7 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
dictionaries. |
| Source of term |
aat |
| 9 (RLIN) |
96209 |
| 655 #7 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Laboratory manuals. |
| Source of term |
lcgft |
| 655 #7 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Dictionaries. |
| Source of term |
lcgft |
| 9 (RLIN) |
96209 |
| 655 #7 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Manuels de laboratoire. |
| Source of term |
rvmgf |
| 9 (RLIN) |
966128 |
| 655 #7 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Dictionnaires. |
| Source of term |
rvmgf |
| 9 (RLIN) |
600163 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mbikay, Majambu. |
| 9 (RLIN) |
88787 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Seidah, Nabil G. |
| 9 (RLIN) |
88788 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Print version: |
| Title |
Proprotein convertases. |
| Place, publisher, and date of publication |
New York, NY : Humana Press, ©2011 |
| International Standard Book Number |
1617792039 |
| Record control number |
(DLC) 2011933260 |
| -- |
(OCoLC)728580600 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Methods in molecular biology ; |
| Volume number/sequential designation |
volume 768. |
| International Standard Serial Number |
1064-3745 |
| 9 (RLIN) |
86007 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-61779-204-5">https://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-61779-204-5</a> |
| 936 ## - OCLC/CONSER MISCELLANEOUS DATA (OCLC); PIECE USED FOR CATALOGING (pre-AACR2) (RLIN) |
|---|
| OCLC control number(s) of parallel record(s) (OCLC); Piece used for cataloging, PUC (RLIN) |
BATCHLOAD |
| 938 ## - |
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YBP Library Services |
| -- |
YANK |
| -- |
7476227 |
| 994 ## - |
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| -- |
92 |
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ATIST |