Antibody drug discovery / (Record no. 708459)

MARC details
000 -LEADER
fixed length control field 05547cam a2200841Ma 4500
001 - CONTROL NUMBER
control field ocn785777976
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240925154147.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cn|||||||||
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120227s2012 enka ob 001 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency E7B
Language of cataloging eng
Description conventions pn
Transcribing agency E7B
Modifying agency OCLCQ
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-- OCLCO
019 ## -
-- 780036541
-- 858227947
-- 1086526656
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781848166295
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 184816629X
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Canceled/invalid ISBN 1848166281
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Canceled/invalid ISBN 9781848166288
035 ## - SYSTEM CONTROL NUMBER
System control number 516762
-- (N$T)
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)785777976
Canceled/invalid control number (OCoLC)780036541
-- (OCoLC)858227947
-- (OCoLC)1086526656
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QP519.9.I44
Item number A68 2012eb
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 071000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.3/7
Edition number 22
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
245 00 - TITLE STATEMENT
Title Antibody drug discovery /
Statement of responsibility, etc. Clive R. Wood, editor.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. London :
Name of publisher, distributor, etc. Imperial College Press,
Date of publication, distribution, etc. 2012.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (xv, 473 pages) :
Other physical details illustrations (some color)
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
490 1# - SERIES STATEMENT
Series statement Molecular medicine and medicinal chemistry ;
Volume/sequential designation v. 4
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Ch. 1. Humanization of antibodies / Olivier Leger and Jose W. Saldanha -- ch. 2. Selection and screening of antibody phage display libraries / David R. Buckler [and others] -- ch. 3. Affinity maturation approaches for antibody lead optimization / David Lowe, Trevor Wilkinson and Tristan J. Vaughan -- ch. 4. Transgenic mice rearranging human antibodies / Sean Stevens -- ch. 5. Isotype selection and Fc engineering: design and construction of fit-for-purpose therapeutic antibodies / William R. Strohl -- ch. 6. Antibody expression from bacteria to transgenic animals / Paul Stephens and Berni M. Sweeney -- ch. 7. Current trends in antibody purification and lead selection / Jie Chen and Andrew Nixon -- ch. 8. Design and application of immunoconjugates for cancer therapy / Sherif El Sheikh [and others] -- ch. 9. Dual-targeting bispecific antibodies as new therapeutic modalities for cancer / Zhenping Zhu -- ch. 10. Antibody fragments and alternate protein scaffolds / Lioudmila Tchistiakova [and others].
520 ## - SUMMARY, ETC.
Summary, etc. Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been developed by select centers of excellence in industry and academia, and are continually being fine tuned in the race to identify the best antibody-based drug candidates and accelerate their paths to patients. The objective of this volume is to provide a series of guides to those evaluating and preparing to enter particular areas within the field and to offer specialized perspectives to established researchers. The chapters set into context the significance of key developments and important considerations for selecting different approaches, such as antibody humanization, isotype selection, lead candidate selection criteria and protein production. All contributors to this work are experts in their fields and many have played pivotal roles in the creation of these technologies.
590 ## - LOCAL NOTE (RLIN)
Local note WorldCat record variable field(s) change: 650
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoenzyme technique.
9 (RLIN) 137117
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Antibody-drug conjugates.
9 (RLIN) 82831
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunology
General subdivision Technique.
9 (RLIN) 143808
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug development.
9 (RLIN) 80817
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical biotechnology.
9 (RLIN) 86925
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoglobulins.
9 (RLIN) 79914
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Antibodies
9 (RLIN) 79912
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoglobulins
9 (RLIN) 79914
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug Discovery
9 (RLIN) 84661
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoenzyme Techniques
9 (RLIN) 79869
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Serum Globulins
9 (RLIN) 79916
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Technique immuno-enzymatique.
9 (RLIN) 137118
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Conjugués anticorps-médicament.
9 (RLIN) 82835
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunologie
General subdivision Technique.
9 (RLIN) 1020491
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Médicaments
General subdivision Développement.
9 (RLIN) 105681
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biotechnologie pharmaceutique.
9 (RLIN) 133789
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Anticorps.
9 (RLIN) 119387
650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoglobulines.
9 (RLIN) 103712
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element MEDICAL
General subdivision Pharmacology.
Source of heading or term bisacsh
9 (RLIN) 80262
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Antibody-drug conjugates.
Source of heading or term fast
Authority record control number (OCoLC)fst00810453
9 (RLIN) 82831
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drug development.
Source of heading or term fast
Authority record control number (OCoLC)fst00898670
9 (RLIN) 80817
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunoenzyme technique.
Source of heading or term fast
Authority record control number (OCoLC)fst00967945
9 (RLIN) 137117
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Immunology
General subdivision Technique.
Source of heading or term fast
Authority record control number (OCoLC)fst00968026
9 (RLIN) 143808
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical biotechnology.
Source of heading or term fast
Authority record control number (OCoLC)fst01060106
9 (RLIN) 86925
655 #0 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
9 (RLIN) 396
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
9 (RLIN) 396
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wood, Clive R.
9 (RLIN) 629399
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Print version:
Title Antibody drug discovery.
Place, publisher, and date of publication London : Imperial College Press, ©2012
International Standard Book Number 9781848166288
Record control number (OCoLC)776670289
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Molecular medicine and medicinal chemistry ;
Volume number/sequential designation v. 4.
9 (RLIN) 583454
856 40 - ELECTRONIC LOCATION AND ACCESS
Materials specified EBSCOhost
Uniform Resource Identifier <a href="https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=516762">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=516762</a>
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994 ## -
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Holdings
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