MARC details
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06964cam a2200709Mi 4500 |
| 001 - CONTROL NUMBER |
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on1055262923 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20240925165336.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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m d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr |n||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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181003s2019 enk o 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
YDX |
| Language of cataloging |
eng |
| Description conventions |
pn |
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YDX |
| Modifying agency |
OPELS |
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EBLCP |
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N$T |
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OCLCF |
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OCLCQ |
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MERER |
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OCLCQ |
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UHL |
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OCLCQ |
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OCLCO |
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OCLCA |
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OCLCQ |
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OCLCA |
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OCLCQ |
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S2H |
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OCLCO |
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REDDC |
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OCLCA |
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TEU |
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OCLCQ |
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COM |
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OCLCO |
| 019 ## - |
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1055043001 |
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1105175151 |
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1105563112 |
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1113291940 |
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1118508330 |
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1124322252 |
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1162061852 |
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1229130895 |
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1235839922 |
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1257368298 |
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1311343720 |
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1311348665 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780128140024 |
| Qualifying information |
(electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
012814002X |
| Qualifying information |
(electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Canceled/invalid ISBN |
0128140011 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Canceled/invalid ISBN |
9780128140017 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
1789754 |
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(N$T) |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)1055262923 |
| Canceled/invalid control number |
(OCoLC)1055043001 |
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(OCoLC)1105175151 |
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(OCoLC)1105563112 |
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(OCoLC)1113291940 |
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(OCoLC)1118508330 |
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(OCoLC)1124322252 |
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(OCoLC)1162061852 |
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(OCoLC)1229130895 |
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(OCoLC)1235839922 |
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(OCoLC)1257368298 |
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(OCoLC)1311343720 |
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(OCoLC)1311348665 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RS201.N35 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
QV 785 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED |
| Subject category code subdivision |
071000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
615.1/9 |
| Edition number |
23 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
MAIN |
| 245 00 - TITLE STATEMENT |
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| Title |
Brain targeted drug delivery systems : |
| Remainder of title |
a focus on nanotechnology and and nanoparticulates / |
| Statement of responsibility, etc. |
edited by Huile Gao, Xiaoling Gao. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc. |
London : |
| Name of publisher, distributor, etc. |
Academic Press, |
| Date of publication, distribution, etc. |
©2019. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Front Cover; Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates; Copyright; Dedication; Contents; Contributors; Preface; Chapter 1: Introduction and overview; 1. Is it possible to deliver drugs to brain?; 2. What's the major concerns of brain-targeted DDS?; 3. Conclusion; Part I: Physiology and principles for brain targeting drug delivery; Chapter 2: Anatomy and physiology of blood-brain barrier; 1. Introduction; 2. Concept of blood-brain barrier; 3. Neurovascular unit; 3.1. Occludin; 3.2. Claudin; 3.3. Adhesion junctions; 3.4. Junctional adhesion molecules. |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
3.5. Accessory proteins3.6. Pericytes; 3.7. Neurons; 3.8. Extracellular matrix; 4. Role of astrocytes; 5. Transportation across blood-brain barrier; 6. Types of transport systems at blood-brain barrier; 6.1. Amino acid transport; 6.2. Hexose transport system; 6.3. Monocarboxylate transporter system; 6.4. Organic anion transporter family; 6.5. Organic cation transporter (OCT and OCTN) family; 6.6. Transport of nucleosides; 6.7. Transport of peptides; 6.8. Transport of macromolecules; 6.9. Transport of ions; 6.10. Transcytosis of macromolecules; 7. Conclusions; References. |
| 505 8# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Chapter 3: Recent progress in blood-brain barrier transportation research1. Introduction; 2. Overview of the transport mechanisms at the BBB; 2.1. Carrier-mediated transcytosis; 2.1.1. Glucose transporters; 2.1.2. Large neutral amino acid transporter 1; 2.1.3. Monocarboxylate transporter 1; 2.2. Receptor-mediated transport; 2.2.1. Transferrin receptor; 2.2.2. Insulin receptor; 2.2.3. Low-density lipoprotein receptor-related protein; 2.3. Adsorptive-mediated transcytosis; 3. Strategies for improving CNS delivery of therapeutics; 3.1. Enhanced paracellular transport. |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
3.2. Improving physicochemical properties of CNS-active drugs3.3. Drug modification with targeting moieties; 3.4. Nanocarrier-based drug delivery; 3.5. Cell-based drug delivery; 4. Future perspectives; References; Chapter 4: In vitro and in vivo models of BBB to evaluate brain targeting drug delivery; 1. Introduction; 2. The neurovascular unit; 2.1. Endothelial cells; 2.2. Pericytes; 2.3. Astrocytes; 2.4. Molecular structure of the junction; 2.4.1. Tight junctions; 2.4.2. Adherens junction; 3. Movement through the blood-brain barrier; 3.1. Passive diffusion; 3.2. Carrier-mediated transport. |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
3.3. Active efflux pumps3.4. Transcytosis; 3.5. Cell-mediated transport; 4. In vitro models of BBB for assessing drug delivery; 4.1. Methods for measuring permeability; 4.1.1. TEER (trans-endothelial electric resistance) measurement; 4.1.2. FITC-dextran and sodium fluorescein; 4.1.3. Lucifer yellow; 4.1.4. Evans blue dye; 4.1.5. Horseradish peroxidase (HRP); 4.1.6. Mannitol/sucrose/inulin (radiolabeled); 4.2. In vitro models; 4.2.1. Noncell-based (synthetic) in vitro models; 4.2.1.1. Immobilized artificial membrane (IAM) chromatography; 4.2.1.2. Parallel artificial membrane permeability assay. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references and index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers; Discusses key points in developing brain targeting drug delivery systems; Summarizes and presents currently available strategies for brain targeting drug delivery; Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research. |
| 590 ## - LOCAL NOTE (RLIN) |
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| Local note |
WorldCat record variable field(s) change: 650 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Nanoparticles. |
| 9 (RLIN) |
6289 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Drug delivery systems. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Blood-brain barrier. |
| 9 (RLIN) |
80961 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Nanoparticles |
| General subdivision |
therapeutic use |
| 9 (RLIN) |
86927 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Drug Delivery Systems |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Blood-Brain Barrier |
| 9 (RLIN) |
80961 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Nanoparticles |
| 9 (RLIN) |
6289 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Nanoparticules. |
| 9 (RLIN) |
106862 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Systèmes d'administration de médicaments. |
| 9 (RLIN) |
969986 |
| 650 #6 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Barrière hémato-encéphalique. |
| 9 (RLIN) |
111898 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
MEDICAL |
| General subdivision |
Pharmacology. |
| Source of heading or term |
bisacsh |
| 9 (RLIN) |
80262 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Drug delivery systems. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst00898667 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Nanomedicine. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst01744350 |
| 9 (RLIN) |
86424 |
| 655 #0 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Electronic books. |
| 9 (RLIN) |
396 |
| 655 #4 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Electronic books. |
| 9 (RLIN) |
396 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gao, Huile. |
| 9 (RLIN) |
200206 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gao, Xiaoling. |
| 9 (RLIN) |
207265 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Print version: |
| Title |
Brain targeted drug delivery systems. |
| Place, publisher, and date of publication |
London : Academic Press, ©2019 |
| International Standard Book Number |
0128140011 |
| -- |
9780128140017 |
| Record control number |
(OCoLC)1028228863 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Materials specified |
EBSCOhost |
| Uniform Resource Identifier |
<a href="https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1789754">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1789754</a> |
| 938 ## - |
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ProQuest Ebook Central |
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EBLB |
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EBL5522117 |
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EBSCOhost |
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EBSC |
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1789754 |
| 938 ## - |
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YBP Library Services |
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YANK |
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15733198 |
| 994 ## - |
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92 |
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N$T |