MARC details
| 000 -LEADER |
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| fixed length control field |
03394cam a22003732c 4500 |
| 001 - CONTROL NUMBER |
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| control field |
1822507065 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-627 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250716135259.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr uuu---uuuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
221115s2022 sz |||||o 00| ||eng c |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783031114564 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(DE-627)1822507065 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(DE-599)KEP082568774 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(DE-He213)978-3-031-11454-0 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(DE-627-1)082568774 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
DE-627 |
| Language of cataloging |
ger |
| Transcribing agency |
DE-627 |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 044 ## - COUNTRY OF PUBLISHING/PRODUCING ENTITY CODE |
|---|
| ISO country code |
XA-CH |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
571.6 |
| Edition number |
23 |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
DNA Methyltransferases - Role and Function / |
| Statement of responsibility, etc. |
edited by Albert Jeltsch, Renata Z. Jurkowska |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
2nd ed. 2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Cham : |
| Name of producer, publisher, distributor, manufacturer |
Springer International Publishing, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Cham |
| Name of producer, publisher, distributor, manufacturer |
Imprint: Springer |
| Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
IX, 562 p. 1 illus. |
| 490 0# - SERIES STATEMENT |
|---|
| Series statement |
Advances in Experimental Medicine and Biology |
| Volume/sequential designation |
1389 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Chapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation – from past achievements to future challenges -- Chapter 2.Bacterial DNA Methylation and Methylomes -- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases -- Chapter 4. Enzymology of Mammalian DNA Methyltransferases -- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase -- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases -- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics -- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark -- Chapter 9. Pathways of DNA Demethylation -- Chapter 10. Structure and Function of TET Enzymes -- Chapter 11.Proteins That Read DNA Methylation -- Chapter 12. Recent advances on DNA base flipping – a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer -- Chapter 14. DNMTs and DNA damage -- Chapter 15. Role of DNMTs in brain -- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation -- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach? -- Chapter 19. DNA Labeling Using DNA Methyltransferases. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. As the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Cytology. |
| 9 (RLIN) |
196 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Epigenetics. |
| 9 (RLIN) |
87814 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medical genetics. |
| 9 (RLIN) |
4482 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Enzymology. |
| 9 (RLIN) |
81044 |
| 951 ## - EQUIVALENCE OR CROSS-REFERENCE-GEOGRAPHIC NAME/AREA NAME [OBSOLETE] [CAN/MARC only] |
|---|
| Geographic name |
BO |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |