Programmed cell death. Part A, General principles for studying cell death / edited by Roya Khosravi-Far, Zahra Zakeri, Richard A. Lockshin, Mauro Piacentini.

Includes bibliographical references and index.

Analyzing morphological and ultrastructural features in cell death / A. Tinari [and others] -- Evaluation of some cell death features by real time real space microscopy / S.S. Smaili, T.R. Rosenstock and Y.T. Hsu -- Analysis of apoptotic pathways by multiparametric flow cytometry : application to HIV infection / H. Lecoeur [and others] -- Methods to analyze the palmitoylated CD95 high molecular weight death-inducing signaling complex / C. Feig and M.E. Peter -- Immunomagnetic isolation of tumor necrosis factor receptosomes / V. Tchikov and S. Schutze -- Analyzing lipid raft dynamics during cell apoptosis / W. Malorni [and others] -- Apoptosome assembly / Y. Shi -- Caspases : determination of their activities in apoptotic cells / A. Vaculova and B. Zhivotovsky -- Lysosomes in apoptosis / S. Ivanova [and others] -- More than two sides of a coin? : how to detect the multiple activities of type 2 transglutaminase / C. Rodolfo [and others] -- Granzymes and cell death / D. Martinvalet, J. Thiery and D. Chowdhury -- Investigation of the proapoptotic BCL-2 family member bid on the crossroad of the DNA damage response and apoptosis / S.S. Zinkel -- Assembly, purification, and assay of the activity of the ASC pyroptosome / T. Fernandes-Alnemri and E.S. Alnemri -- Nucleases in programmed cell death / K. Kawane and S. Nagata -- Detection of autophagy in cell death / Z. Zakeri, A. Melendez and R.A. Lockshin -- Methods for distinguishing apoptotic from necrotic cells and measuring their clearance / D.V. Krysko [and others] -- Two-dimensional gel-based analysis of the demolition phase of apoptosis / A.U. Luthi, S.P. Cullen and S.J. Martin -- Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis / L. Galluzzi [and others] -- Oxidative lipidomics of programmed cell death / V.A. Tyurin [and others] -- Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivo / K. Zhang and R.J. Kaufman -- Organelle intermixing and membrane scrambling in cell death / M. Degli Esposti -- Mechanisms and methods in glucose metabolism and cell death / Y. Zhao [and others].

Print version record.

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on the latest techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.

English.