Aging of the genome : the dual role of DNA in life and death / Jan Vijg.

By:

Vijg, Jan

Material type: Text

TextPublication details: Oxford ; New York : Oxford University Press, 2007.Description: 1 online resource (x, 372 pages) : illustrationsContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9780191524585
0191524581
9781429469937
1429469935
0198569238
9780198569237

Subject(s): Additional physical formats: Print version:: Aging of the genome.DDC classification:

612.8 22

LOC classification:

QP86 .V537 2007eb

NLM classification:

2007 C-828
WT 104

Online resources:

EBSCOhost

Contents:

The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life?

Summary: Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol.

Holdings ( 1 )
Title notes ( 5 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode	Item holds
eBook	e-Library	EBSCO Science		Available

Total holds: 0

Print version record.

Includes bibliographical references (pages 309-351) and index.

The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life?

Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol.

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