TY - BOOK AU - Wu,Cathy H. AU - Chen,Chuming TI - Bioinformatics for comparative proteomics T2 - Springer protocols SN - 9781607619772 AV - QP551 .B56 2011 U1 - 572/.60285 22 PY - 2011/// CY - New York PB - Humana Press KW - Proteomics KW - Data processing KW - Biochemistry KW - Genomics KW - Biology KW - Proteins KW - Life sciences KW - Information storage and retrieval systems KW - Chemistry KW - Mass spectrometry KW - Physical sciences KW - Publication Formats KW - Databases as Topic KW - Chemistry Techniques, Analytical KW - Biological Science Disciplines KW - Information Storage and Retrieval KW - Information Systems KW - Investigative Techniques KW - Amino Acids, Peptides, and Proteins KW - Publication Characteristics KW - Genetics KW - Databases, Factual KW - Mass Spectrometry KW - Laboratory Manuals KW - Computational Biology KW - Proteome KW - Analytical, Diagnostic and Therapeutic Techniques and Equipment KW - Natural Science Disciplines KW - Information Science KW - Medical Informatics Applications KW - Chemicals and Drugs KW - Disciplines and Occupations KW - Medical Informatics KW - Protéomique KW - Informatique KW - Biochimie KW - Génomique KW - Biologie KW - Protéines KW - Sciences de la vie KW - Systèmes d'information KW - Chimie KW - Spectrométrie de masse KW - Bio-informatique KW - Protéomes KW - Sciences physiques KW - Médecine KW - biochemistry KW - aat KW - biology KW - protein KW - biological sciences KW - chemistry KW - mass spectrometry KW - physical sciences KW - fast KW - bioinformatics KW - eiwitexpressieanalyse KW - proteomics KW - Bioinformatics (General) KW - Bioinformatica (algemeen) KW - Laboratory Manual KW - Internet Resources KW - Laboratory manuals KW - lcgft KW - Manuels de laboratoire KW - rvmgf N1 - Includes bibliographical references and index; Protein bioinformatics databases and resources -- A guide to UniProt for protein scientists -- Interpro protein classification -- Reactome knowledgebase of human biological pathways and processes -- eFIP: A tool for mining functional impact of phosphorylation from literature -- A tutorial on protein ontology resources for proteomic studies -- Structure-guided rule-based annotation of protein functional sites in UniProt knowledgebase -- Modeling mass spectrometry-based protein analysis -- Protein identification from tandem mass spectra by database searching -- LC-MS data analysis for differential protein expression detection -- Protein identification by spectral networks analysis -- Software pipeline and data analysis for ms/ms proteomics: The trans-proteomic pipeline -- Analysis of high-throughput ELISA microarray data -- Proteomics databases and repositories -- Preparing molecular interaction data for publication -- Submitting proteomics data to PRIDE using PRIDE converter -- Automated data integration and determination of posttranslational modifications with the protein inference engine -- An integrated top-down and bottom-up strategy for characterization of protein isoforms and modifications -- Phosphoproteome resource for systems biology research -- Protein-centric data integration for functional analysis of comparative proteomics data -- Integration of proteomic and metabolomic profiling as well as metabolic modeling for the functional analysis of metabolic networks -- Time series proteome profiling N2 - With the rapid development of proteomic technologies in the life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. In Bioinformatics for Comparative Proteomics, experts in the field highlight the current status, challenges, open problems, and future trends for developing bioinformatics tools and resources for comparative proteomics research in order to deliver a definitive reference providing both the breadth and depth needed on the subject. Structured in three major sections, this detailed volume covers basic bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics data analysis, and integrated bioinformatics systems and approaches for studying comparative proteomics in the systems biology context. Written for the highly successful Methods in Molecular Biology series, the contributions in this book provide the meticulous, step-by-step description and implementation advice that is crucial for getting optimal results in the lab. Comprehensive and easy-to-use, Bioinformatics for Comparative Proteomics serves all readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods and future trends in proteomics data analysis, and comparative proteomics in systems biology UR - https://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-60761-977-2 ER -