TY  - BOOK
AU  - Kuo,Lawrence C.
AU  - Shafer,Jules A.
TI  - Retroviral proteases
T2  - Methods in enzymology,
SN  - 0121821420
AV  - QP601 M49 vol. 241
U1  - 547.758 20
PY  - 1994///
CY  - San Diego
PB  - Academic Press
KW  - Proteolytic enzymes
KW  - Retroviruses
KW  - Enzymes
KW  - HIV (Viruses)
KW  - Aspartic proteinases
KW  - Retroviridae
KW  - enzymology
KW  - Aspartic Acid Endopeptidases
KW  - Peptide Hydrolases
KW  - HIV
KW  - Enzymes protéolytiques
KW  - Rétrovirus
KW  - Virus de l'immunodéficience humaine
KW  - Endopeptidases aspartiques
KW  - fast
KW  - Proteasen
KW  - gnd
KW  - Retroviren
KW  - Aufsatzsammlung
KW  - Proteïnasen
KW  - gtt
KW  - Retrovirussen
KW  - Enzymologia
KW  - podręczniki laboratoryjne
KW  - jhpk
KW  - Related to
KW  - Viruses
KW  - Electronic books
N1  - Includes bibliographical references and indexes; 1. Expression Systems for Retroviral Proteases; Jeffrey Stebbins and Christine Debouck --; 2. Genetic Approaches Designed to Minimize Cytotoxicity of Retroviral Protease; C.J. Rizzo and B.D. Korant --; 3. Host Strain Selection for Bacterial Expression of Toxic Proteins; Elizabeth Chen --; 4. Assay Methods for Retroviral Proteases; Christopher U.T. Hellen --; 5. Analysis of Human Immunodeficiency Virus Type 1 Protease Activity in Eukaryotic and Bacterial Cells; Andrew H. Kaplan, Marianne Manchester, Lorraine Everitt and Ronald Swanstrom --; 6. Synthetic Approaches to Continuous Assays of Retroviral Proteases; Grant A. Krafft and Gary T. Wang --; 7. Identification, Purification, and Cell Culture Assays of Retroviral Proteases; Klaus von der Helm, Sigrio Seelmeier, Alexei Kisselev and Hans Nitschko --; 8. Stability of Dimeric Retroviral Proteases; Paul L. Darke; 9. Use of Steady State Kinetic Methods to Elucidate the Kinetic and Chemical Mechanisms of Retroviral Proteases; Thomas D. Meek, Evelyn J. Rodriguez and Thelma S. Angeles --; 10. X-Ray Structures of Retroviral Proteases and Their Inhibitor-Bound Complexes; Dagmar Ringe --; 11. Probing Structure-Function Relationships in Human Immunodeficiency Virus Type 1 Protease via Molecular Dynamics Simulation; William E. Harte, Jr. and David L. Beveridge --; 12. Relationships of Human Immunodeficiency Virus Protease with Eukaryotic Aspartic Proteases; Xin-Li Lin, Ying-Zhang Lin and Jordan Tang --; 13. Processing of Retroviral Gag Polyproteins: An in Vitro Approach; Carol Carter and Gabriele Zybarth --; 14. Subsite Preferences of Retroviral Proteinases; Ben M. Dunn, Alla Gustchina, Alexander Wlodawer and John Kay --; 15. Specificity of Retroviral Proteases: An Analysis of Viral and Nonviral Protein Substrates; Alfredo G. Tomasselli and Robert L. Heinrikson; 16. Rapid Determination of Endoprotease Specificity Using Peptide Mixtures and Edman Degradation Analysis; Frank R. Masiarz and Bruce A. Malcolm --; 17. Design of Tight-Binding Human Immunodeficiency Virus Type 1 Protease Inhibitors; Joseph P. Vacca --; 18. Design of Symmetry-Based, Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease; Dale J. Kempf --; 19. Advances in Automated Docking Applied to Human Immunodeficiency Virus Type 1 Protease; Michael D. Miller, Robert P. Sheridan, Simon K. Kearsley and Dennis J. Underwood --; 20. Use of Molecular Dynamics and Free Energy Perturbation Calculations in Anti-Human Immunodeficiency Virus Drug Design; Margaret A. McCarrick and Peter Kollman --; 21. Qualitative Study of Drug Resistance in Retroviral Protease Using Structural Modeling and Site-Directed Mutagenesis; J. Chris Culberson, Bruce L. Bush and Vinod V. Sardana; Electronic reproduction; [Place of publication not identified]; HathiTrust Digital Library; 2011
N2  - Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design
UR  - https://www-sciencedirect-com.libraryproxy.ist.ac.at/science/bookseries/00766879/241
ER  -