TY - BOOK AU - Müller-Reichert,Thomas AU - Verkade,Paul TI - Correlative light and electron microscopy IV T2 - Methods in cell biology SN - 9780128220597 AV - QH212.E4 C67 2021 U1 - 570.2823 23 PY - 2021/// CY - Cambridge, MA PB - Academic Press KW - Electron microscopy KW - Light KW - Microscopy KW - trends KW - Microscopy, Electron KW - Microscopie électronique KW - Lumière KW - electron microscopy KW - aat KW - light (energy) KW - fast KW - Internet Resources KW - Index not Present N2 - Abstract: Correlative light and electron microscopy (CLEM) combines the strengths of light microscopy (LM) and electron microscopy (EM) to pin-point and visualize cellular or macromolecular structures. However, there are many different imaging modalities that can be combined in a CLEM workflow, creating a vast number of combinations that can overwhelm new-comers to the field. Here, we offer a conceptual framework to help guide the decision-making process for choosing the CLEM workflow that can best address your research question, based on the answer to five questions UR - https://www-sciencedirect-com.libraryproxy.ist.ac.at/science/bookseries/0091679X/162 ER -