TY - BOOK AU - Ackerman,Margaret E. AU - Nimmerjahn,Falk TI - Antibody Fc: linking adaptive and innate immunity SN - 9780123948182 AV - Q186.7 U1 - 571.9/67 23 PY - 2014/// CY - London, Waltham, MA, San Diego, CA PB - Elsevier/Academic Press KW - Immunoglobulins KW - Antibody diversity KW - Natural immunity KW - Receptors, Fc KW - immunology KW - Adaptive Immunity KW - Antibodies KW - therapeutic use KW - Immunity, Innate KW - physiology KW - Antibody Diversity KW - Anticorps KW - Diversité KW - Immunité naturelle KW - SCIENCE KW - Life Sciences KW - Anatomy & Physiology KW - bisacsh KW - fast KW - Electronic books N1 - Includes bibliographical references and index; 1. Effector mechanisms -- 2. Effector cells -- 3. FcR -- 4. Variability of the Fc domain -- 5. Genetic associations -- 6. Evolving areas N2 - Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=486009 ER -