Wound regeneration and repair : methods and protocols / edited by Robert G. Gourdie, Virginia Tech Carilion Research Institute, Roanoke, VA, USA, Tereance A. Myers, School of Pharmacy, MCPHS University, Worcester, MA, USA.

Includes bibliographical references and index.

An in vivo model system for evaluation of the host response to biomaterials / Brian Sicari, Neill Turner, and Stephen F. Badylak -- Urothelial cell culture / Yuanyuan Zhang and Anthony Atala -- Cell-populated collagen lattice contraction model for the investigation of fibroblast collagen interactions / H. Paul Ehrlich and Kurtis E. Moyer -- A tissue-engineered corneal wound healing model for the characterization of reepithelialization / Karine Zaniolo [and four others] -- Adult stem cells in small animal wound healing models / Allison C. Nauta, Geoffrey C. Gurtner, and Michael T. Longaker -- Novel animal models for tracking the fate and contributions of bone marrow derived cells in diabetic healing / Robert C. Caskey and Kenneth W. Liechty -- Neural repair with pluripotent stem cells / Máté Döbrössy and Jan Pruszak -- Cell-based therapies for myocardial repair: emerging role for bone marrow-derived mesenchymal stem cells (MSCs) in the treatment of the chronically injured heart / Jose S. Da Silva and Joshua M. Hare -- A model system for primary abdominal closures / Michael J. Yost [and five others] -- Alternatives for animal wound model systems / Phil Stephens, Matthew Caley, and Matthew Peake -- Novel methods for the investigation of human hypertrophic scarring and other dermal fibrosis / Dariush Honardoust [and four others] -- Study of the human chronic wound tissue: addressing logistic barriers and productive use of laser capture microdissection / Sashwati Roy and Chandan K. Sen -- The wound watch: an objective staging system for wounds in the diabetic (db/db) mouse model / G. Pietramaggiori, S. Scherer, and D.P. Orgill -- Human ex vivo wound healing model / Stojadinovic Olivera and Marjana Tomic-Canic -- Murine models of human wound healing / Jerry S. Chen, Michael T. Longaker, and Geoffrey C. Gurtner -- A corneal scarring model / Daniel J. Gibson and Gregory S. Schultz -- A novel and efficient model of coronary artery ligation in the mouse / Erhe Gao and Walter J. Koch -- Cardiac wound healing post-myocardial infarction: a novel method to target extracellular matrix remodeling in the left ventricle / Rogelio Zamilpa [and seven others] -- Injury models to study cardiac remodeling in the mouse: myocardial infarction and ischemia-reperfusion / Daniel J. Luther, Charles K. Thodeti, and J. Gary Meszaros -- Cryoinjury models of the adult and neonatal mouse heart for studies of scarring and regeneration / Erik G. Strungs [and five others] -- Targeting Wnt signaling to improve wound healing after myocardial infarction / Evangelos P. Daskalopoulos, Ben J.A. Janssen, and W. Matthijs Blankesteijn -- Vascular connexins in restenosis after balloon injury / Sandrine Morel and Brenda R. Kwak -- Gain-of-function assays in the axolotl (Ambystoma mexicanum) to identify signaling pathways that induce and regulate limb regeneration / Jangwoo Lee, Cristian Aguilar, and David Gardiner -- The mouse digit tip: from wound healing to regeneration / Jennifer Simkin [and four others] -- Lower vibrissa follicle amputation: a mammalian model of regeneration / James M. Waters and Allison J. Cowin -- Using Drosophila larvae to study epidermal wound closure and inflammation / Sirisha Burra [and three others] -- Zebrafish cardiac injury and regeneration models: a noninvasive and invasive in vivo model of cardiac regeneration / Michael S. Dickover [and three others] -- Quantifying alterations in cell migration: tracking fluorescently-tagged migrating cells by FACs and live imaging / Rachael Z. Murray -- Examining the role of mast cells in fetal wound healing using cultured cells in vitro / Brian C. Wulff and Traci A. Wilgus -- Assessing macrophage phenotype during tissue repair / Timothy J. Koh, Margaret L. Novak, and Rita E. Mirza -- The use of connexin-based therapeutic approaches to target inflammatory diseases / Simon J. O'Carroll .[and five others] -- Commercialization: patenting and licensing in wound healing and regenerative biology / W. Chip. Hood and David Huizenga -- Translational strategies for the development of a wound healing technology (idea) from bench to bedside / Gautam S. Ghatnekar and Tuan A. Elstrom.

In Wound Regeneration and Repair: Methods and Protocols, expert researchers in the field detail classical and cutting-edge methods for studying wound healing and regeneration. These techniques include cellular and molecular methods, genetic approaches, surgical procedures, clinical advances, drug discovery and delivery modalities, animal and humanized models and new applications in the treatment of pathological wounds in a variety of organs and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, a detailed list of the necessary materials and reagents for each procedure, step-by-step, reproducible laboratory protocols, and a set notes, developed by the authors, for troubleshooting and avoiding known pitfalls. Authoritative and practical, Wound Regeneration and Repair: Methods and Protocols seeks to aid scientists and entrepreneurs in their further study of technologies, models, techniques, and critical new areas and approaches to clinical and commercial translation of research.

Online resource; title from PDF title page (SpringerLink, viewed September 16, 2013).

English.