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001			19160751
003			AT-ISTA
005			20220622161442.0
008			160701t20162016dcuab b 100 0 eng d
010			_a 2016946673
020			_a9780309437875 _q(paperback)
020			_a0309437873 _q(paperback)
035			_a(OCoLC)ocn950893787
040			_aYDXCP _beng _cYDXCP _erda _dBTCTA _dCUS _dOCLCO _dYDX _dOCLCO _dSOI _dTKN _dCOO _dOCLCO _dNRC _dKSU _dOCLCO _dIPL _dOCLCO _dNDD _dZCU _dBTS _dOCLCO _dOCLCA _dCUT _dOCLCO _dDLC
042			_alccopycat
050	0	0	_aQH442.6 _b.W67 2015
060		4	_aQU 550
082	0	4	_a636.0821 _223
111	2		_aWorkshop on the Science, Ethics, and Governance Considerations for Gene Drive Research _d(2015 : _cWashington, D.C.), _jauthor. _9966664
245	1	0	_aGene drives on the horizon : _badvancing science, navigating uncertainty, and aligning research with public values / _cCommittee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct ; Board on Life Sciences, Division on Earth and LIfe Studies, the National Academies of Sciences, Engineering, Medicine.
246	3	0	_aAdvancing science, navigating uncertainty, and aligning research with public values
264		1	_aWashington, D.C. : _bThe National Academies Press, _c[2016]
264		4	_c2016
300			_axii, 217 pages : _billustrations (some color), 1 color map ; _c26 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references.
505	0		_aIntroduction -- The state of knowledge of the molecular biology, population genetics, and ecology of gene-drive modified organisms -- Case studies to examine questions about gene-drive modified organisms -- Charting human values -- Phased testing and scientific approaches to reducing potential harms of gene drives -- Assessing risks of gene-drive modified organisms -- Engaging communities, stakeholders, and publics -- Governing gene drive research and applications -- Gene drives on the horizon: overarching considerations -- Glossary -- Acronyms -- Appendix A: Agenda for the Workshop on the Science, Ethics and Governance Considerations for Gene Drive Research -- Appendix B: List of gene drive webinars -- Appendix C: Mosquito control strategies -- Appendix D: Rodent control strategies -- Appendix E: A brief history of ecological risk assessment -- Appendix F. Biographical sketches of Committee members.
520	1		_a"Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators"-- _cPublisher's description.
650		0	_aGenetic engineering _xMoral and ethical aspects _vCongresses. _96521
650		0	_aGenetic engineering _xHealth aspects _vCongresses. _96522
650		0	_aTransgenic organisms _xRisk assessment _vCongresses. _96523
650		0	_aTransgenic organisms _xMoral and ethical aspects _vCongresses. _96524
650		0	_aEnvironmental health _vCongresses. _96525
650		0	_aGene drives. _96526
650		2	_aClustered Regularly Interspaced Short Palindromic Repeats. _96527
650		2	_aCRISPR-Case Systems. _96528
650		2	_aOrganisms, Genetically Modified. _96529
650		2	_aGenetic Engineering _xethics. _96530
650		2	_aRisk Assessment. _92690
650		2	_aContainment of Biohazards. _96531
650		2	_aSafety. _96532
650		2	_aPublic Health. _96533
650		2	_aEnvironmental Health. _96534
655		2	_aCongresses. _96535
655		7	_aConference papers and proceedings. _2lcgft _96065
710	2		_aNational Academies of Sciences, Engineering, and Medicine (U.S.). _bCommittee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct, _eissuing body. _9966665
906			_a7 _bcbc _ccopycat _d2 _eepcn _f20 _gy-gencatlg
942			_2ddc
999			_c374194 _d374194