000			11338cam a2201801 i 4500
001			ocn847807563
003			OCoLC
005			20250702165902.0
006			m o d
007			cr |||||||||||
008			130612s2013 nyu ob 001 0 eng d
040			_aSCB _beng _erda _epn _cSCB _dSCB _dGW5XE _dFTU _dCOO _dOHS _dOCLCA _dCHVBK _dOCLCF _dOCLCQ _dOCLCO _dVT2 _dYDXCP _dEUW _dOCLCA _dMERER _dOCLCO _dLVT _dOCLCO _dOTZ _dTFH _dOCLCO _dOCLCA _dBUF _dOCLCO _dKIJ _dOCLCO _dOCLCQ _dOCLCO _dCASUM _dOCLCQ _dU3W _dOCLCO _dOCLCQ _dAU@ _dOCLCO _dOCLCQ _dYOU _dOCLCO _dOCLCQ _dOCLCO _dOCLCQ _dOCLCO _dWURST _dOCLCA _dINNDH _dOCLCQ _dOCLCO _dOCLCQ _dOCL _dOCLCO _dWSU _dOCLCO _dOCLCL _dOCLCQ _dOCLCL _dUKAHL _dOCLCQ
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016	7		_a101615424 _2DNLM
016	7		_a016490657 _2Uk
019			_a964917844 _a967626328 _a1005830905 _a1027509227 _a1058452805 _a1081208433 _a1101421243 _a1228620001
020			_a9781627034470 _q(electronic bk.)
020			_a1627034471 _q(electronic bk.)
020			_z9781627034463
020			_z1627034463
024	7		_a10.1007/978-1-62703-447-0 _2doi
029	1		_aAU@ _b000061123401
029	1		_aCHBIS _b009916113
029	1		_aCHVBK _b30355357X
029	1		_aNZ1 _b14927652
035			_a(OCoLC)847807563 _z(OCoLC)964917844 _z(OCoLC)967626328 _z(OCoLC)1005830905 _z(OCoLC)1027509227 _z(OCoLC)1058452805 _z(OCoLC)1081208433 _z(OCoLC)1101421243 _z(OCoLC)1228620001
050		4	_aQH440.5
060		4	_aW1 _bME9616J v.1019 2013
060		4	_aQU 550
072		7	_aPSD _2bicssc
072		7	_aUB _2bicssc
072		7	_aSCI056000 _2bisacsh
080			_a575.113 Q3
082	0	4	_a572.8 _223
049			_aMAIN
245	0	0	_aGenome-wide association studies and genomic prediction / _cedited by Cedric Gondro, Julius van der Werf, Ben Hayes.
264		1	_aNew York : _bHumana Press, _c[2013]
264		4	_c©2013
300			_a1 online resource (xi, 566 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file
347			_bPDF
490	1		_aMethods in molecular biology, _x1940-6029 ; _v1019
504			_aIncludes bibliographical references and index.
588	0		_aOnline resource; title from PDF title page (Springer, viewed June 12, 2013).
505	0	0	_tR for genome-wide association studies / _rCedric Gondro, Laercio R. Porto-Neto, Seung Hwan Lee -- _tDescriptive statistics of data : understanding the data set and phenotypes of interest / _rSonja Dominik -- _tDesigning a GWAS : power, sample size, and data structure / _rRoderick D. Ball -- _tManaging large SNP datasets with SNPpy / _rFaheem Mitha -- _tQuality control for genome-wide association studies / _rCedric Gondro, Seung Hwan Lee, Hak Kyo Lee, Laercio R. Porto-Neto -- _tOverview of statistical methods for genome-wide association studies (GWAS) / _rBen Hayes -- _tStatistical analysis of genomic data / _rRoderick D. Ball -- _tUsing PLINK for genome-wide association studies (GWAS) and data analysis / _rMiguel E. Rentería, Adrian Cortes, Sarah E. Medland -- _tGenome-wide complex trait analysis (GCTA) : Methods, data analyses, and interpretations / _rJian Yang, Sang Hong Lee, Michael E. Goddard, Peter M. Visscher -- _tBayesian methods applied to GWAS / _rRohan L. Fernando, Dorian Garrick -- _tImplementing a QTL detection study (GWAS) using genomic prediction methodology / _rDorian J. Garrick, Rohan L. Fernando -- _tGenome-enabled prediction using the BLR (Bayesian Linear Regression) R-package / _rGustavo de los Campos, Paulino Pérez, Ana I. Vazquez, José Crossa -- _tGenomic best linear unbiased prediction (gBLUP) for the estimation of genomic breeding values / _rSamuel A. Clark, Julius van der Werf -- _tDetecting regions of homozygosity to map the cause of recessively inherited disease / _rJames W. Kijas -- _tUse of ancestral haplotypes in genome-wide association studies / _rTom Druet, Frédéric Farnir -- _tGenotype phasing in populations of closely related individuals / _rJohn M. Hickey -- _tGenotype imputation to increase sample size in pedigreed populations / _rJohn M. Hickey, Matthew A. Cleveland, Christian Maltecca, Gregor Gorjanc, Birgit Gredler, Andreas Kranis -- _tValidation of genome-wide association studies (GWAS) results / _rJohn M. Henshall -- _tDetection of signatures of selection using FST / _rLaercio R. Porto-Neto, Seung Hwan Lee, Hak Kyo Lee, Cedric Gondro -- _tAssociation weight matrix : a network-based approach towards functional genome-wide association studies / _rAntonio Reverter, Marina R.S. Fortes -- _tMixed effects structural equation models and phenotypic causal networks / _rBruno Dourado Valente, Guilherme Jordão Magalhães Rosa -- _tEpistasis, complexity, and multifactor dimensionality reduction / _rQinxin Pan, Ting Hu, Jason H. Moore -- _tApplications of multifactor dimensionality reduction to genome-wide data using the R package 'MDR' / _rStacey Winham -- _tHigher order interactions : detection of epistasis using machine learning and evolutionary computation / _rRonald M. Nelson, Marcin Kierczak, Örjan Carlborg -- _tIncorporating prior knowledge to increase the power of genome-wide association studies / _rAshley Petersen, Justin Spratt, Nathan L. Tintle -- _tGenomic selection in animal breeding programs / _rJulius van der Werf.
520			_a"With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice."-- _cBack cover
546			_aEnglish.
650		0	_aMolecular genetics. _980272
650		0	_aVariation (Biology) _986700
650		0	_aMolecular epidemiology. _985812
650		0	_aGenetics _xTechnique. _984274
650		0	_aDiagnostic services. _986722
650		0	_aBiology. _94937
650		0	_aNational health services. _9144124
650		0	_aDiagnosis. _918367
650		0	_aLife sciences. _9194
650		0	_aPublic health. _96533
650		0	_aMedical care. _9112101
650		0	_aPhysical sciences. _910971
650		0	_aGenomics. _92074
650		0	_aGenetic screening.
650		2	_aMolecular Epidemiology _985812
650		2	_aGenetic Services _986721
650		2	_aEpidemiologic Research Design _980704
650		2	_aGenetic Techniques _92075
650		2	_aComputational Biology
650		2	_aDiagnostic Techniques and Procedures _918366
650		2	_aGenetic Association Studies _987277
650		2	_aGenetics _92539
650		2	_aDiagnostic Services _986722
650		2	_aOligonucleotide Array Sequence Analysis _980562
650		2	_aEpidemiologic Methods
650		2	_aBiology _94937
650		2	_aHealth Services _986726
650		2	_aInvestigative Techniques _912500
650		2	_aSequence Analysis _918393
650		2	_aPreventive Health Services _986727
650		2	_aDiagnosis _918367
650		2	_aHealth Care Facilities, Manpower, and Services _986729
650		2	_aBiological Science Disciplines _912496
650		2	_aAnalytical, Diagnostic and Therapeutic Techniques and Equipment _912503
650		2	_aPublic Health _96533
650		2	_aCommunity Health Services _986728
650		2	_aDelivery of Health Care _934007
650		2	_aEnvironment and Public Health _934006
650		2	_aNatural Science Disciplines _912499
650		2	_aDisciplines and Occupations _912501
650		2	_aGenomics _92074
650		2	_aGenome-Wide Association Study _988832
650		2	_aGenetic Testing _980853
650		2	_aPatient Care _9126103
650		6	_aGénétique moléculaire. _985915
650		6	_aVariation (Biologie) _999556
650		6	_aÉpidémiologie moléculaire. _9958401
650		6	_aGénétique _xTechnique. _984554
650		6	_aBio-informatique. _918088
650		6	_aDiagnostics _xMéthodologie. _9966863
650		6	_aÉtudes d'associations génétiques. _9970556
650		6	_aServices de diagnostics. _9970732
650		6	_aBiologie.
650		6	_aServices de santé. _9425119
650		6	_aDiagnostics. _9469455
650		6	_aSciences de la vie. _982107
650		6	_aSanté publique. _9111983
650		6	_aPrestation de soins. _9966309
650		6	_aSciences physiques. _9966370
650		6	_aGénomique. _925920
650		6	_aÉtude d'association pangénomique. _9970733
650		6	_aDépistage génétique. _9332071
650		6	_aSoins médicaux.
650		7	_abiology. _2aat _94937
650		7	_adiagnosis. _2aat _918367
650		7	_abiological sciences. _2aat _9966371
650		7	_apublic health. _2aat _96533
650		7	_aphysical sciences. _2aat _910971
650		7	_aPublic health _2fast _96533
650		7	_aPhysical sciences _2fast _910971
650		7	_aNational health services _2fast _9144124
650		7	_aMolecular epidemiology _2fast _985812
650		7	_aMedical care _2fast _9112101
650		7	_aLife sciences _2fast _9194
650		7	_aGenomics _2fast _92074
650		7	_aGenetics _xTechnique _2fast _984274
650		7	_aGenetic screening _2fast
650		7	_aDiagnostic services _2fast _986722
650		7	_aDiagnosis _2fast _918367
650		7	_aBiology _2fast _94937
650		7	_aMolecular genetics _2fast _980272
650		7	_aVariation (Biology) _2fast _986700
653	0	0	_agenomica
653	0	0	_agenomics
653	0	0	_abioinformatics
653	0	0	_ahumane genetica
653	0	0	_ahuman genetics
653	1	0	_aGenome informatics
653	1	0	_aGenoominformatica
655		2	_aLaboratory Manual
655		4	_aInternet Resources. _980513
655		7	_aLaboratory manuals. _2lcgft
655		7	_aManuels de laboratoire. _2rvmgf _9966128
700	1		_aGondro, Cedric, _eeditor. _988833
700	1		_aWerf, Julius van der, _eeditor. _988834
700	1		_aHayes, Ben _q(Ben J.), _eeditor. _1https://id.oclc.org/worldcat/entity/E39PCjFWWcbJBkdyXfFpHxwV4q _988835
776	0	8	_iPrint version: _tGenome-wide Association Studies and Genomic Prediction. _dHumana Pr Inc 2013 _z9781627034463 _w(OCoLC)828487816
830		0	_aMethods in molecular biology (Clifton, N.J.) ; _vv. 1019. _x1064-3745
856	4	0	_uhttps://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-62703-447-0
938			_aAskews and Holts Library Services _bASKH _nAH40390821
938			_aYBP Library Services _bYANK _n10842398
994			_a92 _bATIST
999			_c652788 _d652788