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Epigenetic reprogramming during mouse embryogenesis : methods and protocols / edited by Katia Ancelin, Maud Borensztein.

Contributor(s): Material type: TextTextSeries: Methods in molecular biology (Clifton, N.J.) ; v. 2214. | Springer protocols (Series)Publisher: New York, NY : Humana Press, [2021]Description: 1 online resource (1 PDF file (xi, 318 pages)) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781071609583
  • 1071609580
Subject(s): Genre/Form: Additional physical formats: No titleDDC classification:
  • 571.8/6 23
LOC classification:
  • QL957
NLM classification:
  • W1
  • QU 25
Online resources: Abstract: Epigenetic reprogramming is crucial for mammalian development and entails unique changes in the spatial and functional organization of the chromatin landscape. Genome-wide reprogramming occurs at specific developmental stages, in the germline and early embryo, and is critical for generating a totipotent/pluripotent state. Although optimized for mouse embryos, these protocols can be adapted to other mammalian models and organoids in culture. Ultimately, this volume aims to present a comprehensive overview of the methods available to scientists wishing to make new discoveries in the fascinating field of chromatin reprogramming.
Holdings
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eBook eBook e-Library eBook Protocols Available
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Includes bibliographical references and index.

Epigenetic reprogramming is crucial for mammalian development and entails unique changes in the spatial and functional organization of the chromatin landscape. Genome-wide reprogramming occurs at specific developmental stages, in the germline and early embryo, and is critical for generating a totipotent/pluripotent state. Although optimized for mouse embryos, these protocols can be adapted to other mammalian models and organoids in culture. Ultimately, this volume aims to present a comprehensive overview of the methods available to scientists wishing to make new discoveries in the fascinating field of chromatin reprogramming.

Online resource; title from PDF title page (SpringerLink, viewed August 18, 2021).

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